I've been working on implementing Leisa Reichelt's design for the new node add/edit form. Gábor Hojtsy started the process off by creating a patch to move the submit buttons up to the right, and separate the node form into a "Content" and a "Meta" tab. I refined his patch to make the horizontal tabs a reusable form element, and in the current state of the patch, the node form looks as pictured:
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